2025.01.27
In reproductive medicine, every detail matters. From the smallest procedural step to the final outcome, precision, consistency, and efficiency define success. Innovations that simplify processes without compromising results are invaluable—and Cryotec Ready to Use (Cryotec RtU) has been recognized by many clinics as a reliable solution in achieving these goals.
In 2024, clinical comparative data on freezing and thawing using Cryotec RtU and other products were collected from 13 facilities across Japan. The results, which included the freezing and thawing of a total of 1,041 embryos using Cryotec RtU and 1,041 embryos using other products, confirmed that the pregnancy rate with Cryotec RtU was 3.56 percentage points higher than with other products.
But numbers only tell part of the story. The real impact of Cryotec RtU lies in how it has reshaped daily processes, reduced stress on embryologists, and improved consistency across teams. We spoke to leading clinics across Japan to hear their experiences firsthand.
When we asked clinics about their reasons for switching to Cryotec RtU, a common theme emerged: the need to simplify preparation steps, reduce errors, and improve overall efficiency.
Noah ART Clinic Musashikosugi:
“We wanted to reduce the complexity of preparing for the warming procedure without compromising results.”
Women’s Clinic We TOYAMA!:
“We wanted to reduce the cost and time spent on consumables such as tips by eliminating the need for dispensing from vials containing freezing and warming solutions. There is no need for pre-shrink steps in freezing. Clear protocols and the ability to acquire techniques through workshops hosted by your company, making it easier to onboard new staff.”
Kaseki ART Clinic:
“To reduce dispensing time and prevent mistakes. To reduce pressure on embryos that occurs when minimizing drops.”
When we asked clinics whether switching to Cryotec Ready to Use (Cryotec RtU) resolved the challenges they faced, the responses highlighted improvements in embryo quality and overall efficiency.
Kyono ART Clinic:
“Not only did it reduce costs, but centralizing inventory management for plates and reagents also contributed to shortening the working hours of embryologists.”
Kaseki ART Clinic:
“During a workshop, I was told that drops could remain as they were, so the degenerated embryos that became fragile during warming have disappeared after switching to RtU.”
These insights highlight how RtU addressed key challenges, streamlining both technical procedures and day-to-day operations.
Clinics using Cryotec RtU reported consistent survival and pregnancy rates, with some seeing measurable improvements.
Noah ART Clinic Musashikosugi:
“We have been using RtU for over a year, and the survival and pregnancy rates remain comparable to previous results.”
Kyono ART Clinic:
“It’s been about two years. While embryo survival rates remained consistently high, oocyte survival rates improved by 5–10%.”
Women’s Clinic We TOYAMA!:
“We started using RtU in March 2023. The results we submitted to your company last year showed improvements in both survival and pregnancy rates.”
Kaseki ART Clinic:
“One year has passed. The pregnancy rate increased slightly. Degenerative rate decreased (for the reasons stated above)”
These responses show that while some clinics experienced stability in their already high results, others saw meaningful improvements in key performance indicators like oocyte survival rates, pregnancy rates, and reduced degeneration rates.
When we asked clinics about the additional benefits they experienced after switching to Cryotec RtU, their answers highlighted improvements in process efficiency, training, and even the overall workplace atmosphere.
Noah ART Clinic Musashikosugi:
“One major benefit is that there is no longer a need to prepare dishes separately.”
Kyono ART Clinic:
“The viscosity of the reagent makes it easier for beginners to load embryos on devices, which has shortened the training period.”
Women’s Clinic We TOYAMA!:
“With shorter freezing and warming times, even during busy periods, we can carry out tasks with a sense of ease and confidence.”
Kaseki ART Clinic:
“The unsealing process is enjoyable, which lifts my mood during warming and freezing.”
These insights show that the benefits of Cryotec RtU extend beyond technical performance—they also enhance process efficiency, training effectiveness, and workplace positivity, creating a well-rounded improvement across embryology labs.
When we asked clinics about their experience transitioning to Cryotec RtU and whether the learning process was easy or challenging, the responses highlighted clear protocols, effective training, and smooth adaptation across teams.
Noah ART Clinic Musashikosugi:
“We gradually introduced RtU after thoroughly observing the recovery and morphology of discarded embryos. The procedures are simple, with fewer steps, making them easy to learn even for less experienced staff.”
Women’s Clinic We TOYAMA!:
“The transition to the product began after attending hands-on training provided by your company. All three embryologists at the time participated in a workshop held at the Embryology Society Conference, where they learned clear and detailed protocols and were able to ask questions on the spot. This made the transition relatively smooth.
Initially, we were slightly puzzled by the viscosity of the solution, but we quickly adapted. Additionally, whenever we encountered issues or had questions after starting practical use, we received prompt and helpful responses, so no significant problems arose.”
Kaseki ART Clinic:
“When the instructor visited, it was incredibly helpful to have them observe my actual techniques. As the years go by, there are fewer opportunities to compare and refine one’s own techniques with others.”
Switching to a new protocol can pose training challenges, but Cryotec RtU has been widely praised for its ease of implementation and clarity.
For clinics still evaluating whether to switch to Cryotec RtU, the advice from experienced users is resounding:
Noah ART Clinic Musashikosugi:
“If you’re looking to reduce the complexity involved in freezing and warming as much as possible, I believe RtU is worth considering.”
Kyono ART Clinic:
“Once you understand the characteristics of the media and the protocol, the transition is extremely smooth. It has been over two years since we introduced it, and while embryo survival rates, pregnancy rates, and birth rates have not changed significantly, we feel confident that oocyte survival rates have improved beyond previous levels. Above all, once you experience the convenience of blister packs, it’s hard to imagine going back!”
Women’s Clinic We TOYAMA!:
“The transition was smooth, operations became simpler, costs and time were reduced, stress was minimized, and technical gaps between new and experienced staff felt smaller. On top of that, performance improved, so I highly recommend it.”
Cryotec RtU is more than just a product. As users have mentioned, it’s a refined system that allows to improve processes, reduce variability, and deliver results that both embryologists and patients can rely on.
With consistent survival rates, reduced operational stress, and a smoother learning curve for staff, Cryotec RtU isn’t just improving procedures—it’s improving experiences.
At REPROLIFE, we’re proud to support clinics in advancing reproductive medicine. Every embryo represents hope, and every improved procedure brings us closer to supporting families on their journey to parenthood.
For more information about Cryotec Ready to Use, contact us.
